Central Areolar Choroidal Sclerosis : A Histo-Pathological Study

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Central areolar choroidal dystrophy associated with dominantly inherited drusen.

AIM To describe the clinical and genetic aspects of a retinal dystrophy that combines central areolar choroidal dystrophy (CACD) and autosomal dominantly inherited drusen. METHODS The members of three unrelated families who demonstrated the rare combination of CACD and dominant drusen were clinically and angiographically investigated. In addition, DNA samples from the members of these familie...

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Localisation of a gene for central areolar choroidal dystrophy to chromosome 17p.

Central areolar choroidal dystrophy (CACD) is a rare inherited retinal disease which causes progressive profound loss of vision in patients during their 4th decade. We have identified a Northern Irish family with 19 affected individuals in three living generations. We have performed a total genome search and established linkage of CACD in this family to chromosome 17p (multipoint Zmax = 5.65 at...

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Central areolar choroidal dystrophy (CACD) and age-related macular degeneration (AMD): differentiating characteristics in multimodal imaging.

PURPOSE Late-onset central areolar choroidal dystrophy (CACD) may easily be confused with geographic atrophy (GA) in AMD. To detect discerning features, the morphologic changes in CACD patients and in AMD patients were assessed with confocal scanning laser ophthalmoscopy (cSLO), fundus autofluorescence (FAF), and spectral-domain optical coherence tomography (SD-OCT). METHODS A total of 30 CAC...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1953

ISSN: 0007-1161

DOI: 10.1136/bjo.37.3.140